WHO WE ARE

Our Scientists

Els Fieremans

ELS FIEREMANS

Associate Professor

I am a faculty at the Department of Radiology, Center for Biomedical Imaging, New York University School of Medicine, where I spearhead the MRI Biophysics group, together with Dr. Dmitry Novikov. I graduated Magna Cum Laude in Engineering in Physics from Ghent University in 2003, where I subsequently received my PhD in 2008 on Validation Methods for Diffusion Weighted Magnetic Resonance Imaging in Brain White Matter. I was a postdoctoral fellow at the Center for Biomedical Imaging, New York University School of Medicine during 2008-2011. Currently, my research focuses on early biomarkers for neurodegenerative diseases, novel contrasts from time-dependent diffusion MRI, and numerical simulations and design of MRI phantoms.

RESEARCH INTERESTS

  • Monte carlo simulations and physical phantoms
  • Biophysical modeling and subsequent animal validation
  • Design of imaging markers for white matter tract integrity describing axonal loss, demyelination and axonal injury from clinically usable diffusion protocols (e.g., diffusional kurtosis imaging) to assess neurodegenerative diseases including Alzheimer’s, multiple sclerosis, traumatic brain injury, cancer, as well as normal development
  • Multimodal imaging studies in Alzheimer’s pathology using MR-PET
  • Design of imaging markers from time-dependent diffusion in brain, muscular pathologies and prostate cancer

SELECTED PUBLICATIONS

  • Li C, Fieremans E, Novikov DS, Ge Y and Zhang J. Measuring water exchange on a preclinical MRI system using filter exchange and diffusion time dependent kurtosis imaging. (2022) Magn Reson Med. Pubmed Magn Reson Med
  • Bubu OM, Kaur SS, Mbah AK, Umasabor-Bubu OQ, Cejudo JR, Debure L, Mullins AE, Parekh A, Kam K, Osakwe ZT, Williams ET, Turner AD, Glodzik L, Rapoport DM, Ogedegbe G, Fieremans E, de Leon MJ, Ayappa I, Jean-Louis G, Masurkar AV, Varga AW and Osorio RS. Obstructive Sleep Apnea and Hypertension with Longitudinal Amyloid-β Burden and Cognitive Changes. (2022) Am J Respir Crit Care Med. 206, 632-636 Pubmed Am J Respir Crit Care Med
  • Coelho S, Baete SH, Lemberskiy G, Ades-Aron B, Barrol G, Veraart J, Novikov DS and Fieremans E. Reproducibility of the Standard Model of diffusion in white matter on clinical MRI systems. (2022) Neuroimage. 257, 119290 Pubmed Neuroimage PMC Article

AWARDS AND HONORS

  • 2009: Henri Benedictus fellowship, Belgian American Foundation and King Baudouin Foundation
  • 2013: Junior Investigator of the Charleston Conference on Alzheimer’s Disease
  • 2014-2015: Fellow, Raymond and Beverly Sackler Laboratories for Convergence of Physical, Engineering and Biomedical Sciences in Honor of Saul J. Farber